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Morton J Cowan Selected Research

Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)

1/2022Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution.
1/2022Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC.
11/2020Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID) in the US Immunodeficiency Network (USIDNet) Registry.
1/2019Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency.
10/2018SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.
10/2018Advances and highlights in primary immunodeficiencies in 2017.
12/2017Immune reconstitution and survival of 100 SCID patients post-hematopoietic cell transplant: a PIDTC natural history study.
11/2017Long term outcomes of severe combined immunodeficiency: therapy implications.
8/2017Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT.
1/2017Transplacental maternal engraftment and posttransplantation graft-versus-host disease in children with severe combined immunodeficiency.
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Morton J Cowan Research Topics

Disease

34Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/2022 - 01/2008
14Graft vs Host Disease (Graft-Versus-Host Disease)
01/2021 - 12/2002
13Primary Immunodeficiency Diseases
04/2021 - 12/2008
11Infections
01/2022 - 05/2008
6Wiskott-Aldrich Syndrome
01/2020 - 01/2009
5Chronic Granulomatous Disease
01/2022 - 01/2011
5Lymphopenia (Lymphocytopenia)
01/2018 - 05/2008
3Neoplasms (Cancer)
01/2018 - 08/2017
3Reticular dysgenesis
12/2017 - 04/2014
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
11/2016 - 03/2009
3Leukemia
11/2016 - 03/2009
2Hypersensitivity (Allergy)
01/2022 - 02/2007
2X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency)
01/2019 - 05/2008
2Hemoglobinopathies
01/2017 - 09/2014
2Body Weight (Weight, Body)
04/2015 - 11/2013
1Cytopenia
01/2022
1Severe combined immunodeficiency due to adenosine deaminase deficiency
01/2022
1Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive)
01/2022
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2021
1Thrombocytopenia (Thrombopenia)
01/2020
1Thrombocytopenia 1
11/2019
1Hypoxia (Hypoxemia)
10/2018
1Common Variable Immunodeficiency
10/2018
1Avian Reticuloendotheliosis
10/2018
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2018
1Bone Marrow Failure Disorders
01/2018
1Severe combined immunodeficiency with sensitivity to ionizing radiation
01/2018
1Nijmegen Breakage Syndrome
01/2018
1Hemophilia A (Haemophilia)
02/2016
1Nephrotic Syndrome (Syndrome, Nephrotic)
02/2016
1Virus Diseases (Viral Diseases)
11/2015
1Mucopolysaccharidosis I (Hurler Syndrome)
09/2015
1Hematologic Neoplasms (Hematological Malignancy)
04/2015
1DiGeorge Syndrome (Syndrome, DiGeorge)
07/2013
1Inborn Errors Metabolism (Inborn Errors of Metabolism)
09/2012
1Measles
03/2011
1Human Influenza (Influenza)
03/2011
1Whooping Cough (Pertussis)
03/2011
1Mumps
03/2011
1beta-Thalassemia (Cooley's Anemia)
02/2011
1Communicable Diseases (Infectious Diseases)
12/2009

Drug/Important Bio-Agent (IBA)

6Busulfan (Busulfex)FDA Link
01/2022 - 11/2012
4T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2022 - 07/2013
3Adenosine DeaminaseIBA
01/2022 - 10/2018
3Immunoglobulins (Immunoglobulin)IBA
04/2021 - 07/2010
3Proteins (Proteins, Gene)FDA Link
10/2018 - 01/2009
3DNA (Deoxyribonucleic Acid)IBA
01/2018 - 05/2008
3AutoantibodiesIBA
02/2016 - 07/2010
3Alkylating AgentsIBA
01/2014 - 02/2012
2AntibodiesIBA
01/2022 - 11/2015
2AntigensIBA
04/2021 - 09/2014
2fludarabineIBA
10/2017 - 11/2012
2Peptides (Polypeptides)IBA
11/2015 - 04/2012
2Alemtuzumab (Campath)FDA Link
09/2014 - 11/2012
2VaccinesIBA
08/2014 - 07/2013
2Anti-Bacterial Agents (Antibiotics)IBA
08/2014 - 03/2011
2Ficusin (Psoralen)IBA
02/2012 - 12/2002
2HLA Antigens (Human Leukocyte Antigens)IBA
02/2011 - 03/2009
1RNA Splice SitesIBA
01/2022
1Messenger RNA (mRNA)IBA
01/2022
1GlobinsIBA
01/2022
1Intravenous Immunoglobulins (IVIG)FDA Link
04/2021
1Indicators and Reagents (Reagents)IBA
04/2021
1CD40 Ligand (CD40L)IBA
01/2019
1leniolisibIBA
10/2018
1Zinc Finger NucleasesIBA
10/2018
1Phosphatidylinositols (Phosphatidylinositol)IBA
10/2018
1Sirolimus (Rapamycin)FDA Link
10/2018
1Actin-Related Protein 2-3 Complex (Arp2 3 Complex)IBA
10/2018
1DNA Ligase ATPIBA
01/2018
1DNA Ligases (Ligases, DNA)IBA
01/2018
1Methotrexate (Mexate)FDA LinkGeneric
08/2017
1Calcineurin InhibitorsIBA
08/2017
1Biomarkers (Surrogate Marker)IBA
12/2016
1Recombinases (Recombinase)IBA
10/2016
1A-factor (Streptomyces)IBA
02/2016
1DNA-Activated Protein KinaseIBA
11/2015
1Ligases (Synthetase)IBA
11/2015
1EndonucleasesIBA
04/2015
1plerixaforFDA Link
09/2014
1EnzymesIBA
04/2014
1NADPH Oxidases (NAD(P)H oxidase)IBA
01/2011
14- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
01/2011
1Immunoglobulin M (IgM)IBA
07/2010
1Immunoglobulin E (IgE)IBA
07/2010
1Immunoglobulin A (IgA)IBA
07/2010
1ElementsIBA
12/2009
1gamma-Globulins (gamma-Globulin)IBA
12/2009

Therapy/Procedure

26Cell Transplantation
01/2022 - 12/2008
17Hematopoietic Stem Cell Transplantation
01/2019 - 01/2008
16Transplantation
10/2018 - 12/2002
13Therapeutics
01/2022 - 10/2009
8Drug Therapy (Chemotherapy)
01/2019 - 10/2008
2Stem Cell Transplantation
04/2015 - 12/2014
1Kidney Transplantation
01/2019
1Critical Care (Surgical Intensive Care)
09/2015
1Enzyme Replacement Therapy
09/2015
1Immunotherapy
04/2015
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
02/2011
1Homologous Transplantation
09/2010